Searchable abstracts of presentations at key conferences in endocrinology

ea0059p084 | Diabetes & cardiovascular | SFEBES2018

Differential regulation of urinary peptides between men and women at early stages of diabetic nephropathy

Currie Gemma , von Scholten Bernt Johan , Lindhardt Morten , Mary Sheon , Mischak Harald , Rossing Peter , Delles Christian

Background: There are differences in the development of diabetic nephropathy (DN) between men and women but the underlying molecular mechanisms are unknown. The urinary proteome may contain sex-specific biomarkers and thereby identify differentially regulated pathways to DN in men and women.Method: Urine samples were obtained from 157 patients with type 2 diabetes (age, 61 (29–71) years; 120 men and 37 women), preserved renal function (eGFR, 88 &#17...